longevity, aging and its prevention
نویسندگان
چکیده
longevity, aging and its prevention
منابع مشابه
Aging and longevity genes.
The genetics of aging has made substantial strides in the past decade. This progress has been confined primarily to model organisms, such as filamentous fungi, yeast, nematodes, fruit flies, and mice, in which some thirty-five genes that determine life span have been cloned. These genes encode a wide array of cellular functions, indicating that there must be multiple mechanisms of aging. Nevert...
متن کاملLongevity and aging
Research into the biology of aging seeks to understand the basic mechanisms of aging, with the goal of extending the period of life spent free from chronic disease and disability. Aging results from molecular processes that are modulated by genetic and environmental parameters. At least some of these mechanisms of aging are broadly shared across eukaryotic species from yeast to mice, and likely...
متن کاملLongevity pathways and memory aging
The aging process has been associated with numerous pathologies at the cellular, tissue, and organ level. Decline or loss of brain functions, including learning and memory, is one of the most devastating and feared aspects of aging. Learning and memory are fundamental processes by which animals adjust to environmental changes, evaluate various sensory signals based on context and experience, an...
متن کاملAging: miRacles of Longevity?
The inventory of processes that miRNAs regulate has continued to expand since their relatively recent discovery. A new study reveals not only that the expression of miRNAs changes with age, but also that these miRNAs can act in both pro- and anti-longevity regulatory pathways.
متن کاملGenetics and epigenetics of aging and longevity
Evolutionary theories of aging predict the existence of certain genes that provide selective advantage early in life with adverse effect on lifespan later in life (antagonistic pleiotropy theory) or longevity insurance genes (disposable soma theory). Indeed, the study of human and animal genetics is gradually identifying new genes that increase lifespan when overexpressed or mutated: gerontogen...
متن کاملAging and longevity: the IGF-1 enigma.
IGF-1 belongs to the insulin family of peptides and acts as a growth factor in many tissues and tumors. Locally acting isoform of IGF-1 targeted to skeletal muscle enhances muscle growth and differentiation, prevents agerelated muscle atrophy, and potentiates regeneration after injury.1,2 Similarly, cardiac restricted expression of IGF-1 increases the formation of ventricular myocytes, attenuat...
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عنوان ژورنال:
گوارشجلد ۳، شماره ۱۵&۱۶، صفحات ۷۱-۰
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